The
available statistics give a vivid picture of the current
healthcare problems in the country and the future
challenges. The total fertility rate at 8.8 is one of the
highest in the world and although there is a high infant
mortality rate of 109 per 1,000 live births (compared with
6.5 in the UK) the population is growing fast at 3.7% per
annum. The population can be expected to double in 18
years. The most cursory observation shows a high
proportion of children and young people, and 52% of the
population are under the age of 15 (compared with 19% in
the UK). Life expectancy is currently 52 years for males
and 53 for females.
The high infant and maternal
mortality rates (maternal mortality 330 per 100,000 live
births compared with 7 in the UK) give great cause for
concern. Malnutrition and poor infant vaccination coverage
are areas for priority attention, particularly given the
uncertainty of future growth of food and water supplies.
Fortunately population control is now being discussed in
government circles. Contraception is practised by only a
minority of couples (17%), but a range of programmes
integrated with healthcare of mothers and children is
planned to extend contraceptive usage.
A visit to the hospitals in
Sana’a reveals a very different pattern of adult medical
disease to that now seen in the UK. The wards are full of
cases of rheumatic fever and rheumatic heart disease as
well as chronic liver disease due largely to viral
hepatitis, and chronic renal failure. Tuberculosis (often
resistant to standard drug treatment) is a major problem
throughout the country. Tropical diseases such as malaria,
amoebiasis, schistosomiasis and onchocerciasis are common.
Yemen is short of doctors and
nurses. There are about 20 doctors per 100,000 population
(compared with 92 in the UK and 242 in Germany per 100,000
population). The majority are in the towns. Until recently
many medical students were educated abroad (especially in
Russia and Romania) with a few (like Professor Abdulla
Abdulwali Nasher, Minister of Health and President of the
Yemen British Friendship Society) graduating from a
British university. Clearly the longterm solution must be
local education. The Medical School in Aden started in
1975 and in Sana’a in 1983. Both now graduate over 100
students per annum. Links with overseas schools in the UK,
Egypt and Sudan are supporting postgraduate studies and
the university has to be congratulated on starting a Yemen
Medical Journal, which will help with the important task
of keeping graduate doctors up-to-date in a fast moving
world.
I have been privileged over the
last 10 years to collaborate in a range of projects with
my Yemeni colleagues, particularly Professor Abdulla
Gunaid, Professor Abdulla Abdulwali Nasher and Dr
Abdulkader el-Guneid. The areas covered reflect my
personal training and interest. New fields are opening up
with the help of other specialists.
Qat
The leaves of this plant (Catha
edulis Forsk.) contain a range of chemicals but it is
Cathinone which is chemically related to amphetamine which
is probably responsible for the pleasurable stimulant
effect on the brain. Unwanted side effects may include
constipation, lack of appetite, sexual disfunction and
difficulty with micturition in the male. We have shown
that Cathinone acts on smooth muscle to produce these
effects and have demonstrated delay in stomach emptying
after a meal as well as an effect on the bladder neck
which is completely reversed by alpha 1 blocking drugs
(widely used by British men with mild prostatic problems).
Cancer
Cancer of the oesophagus and
stomach are far more common in Yemen than in western
Europe. Factors responsible include dietary deficiencies
of antioxidant vitamins, smoking and qat chewing. The role
of pesticides and carcinogens in food is being researched.
An important cause of cancer in
the stomach is chronic infection with the bacteria
Helicobacter pylori. It is probably spread by contaminated
food and water and is thought usually to be acquired in
childhood. This organism is also well known to cause
stomach and duodenal ulcers. We found the bug present in
the majority of Yemenis tested. We are trying to work out
an effective and cheap drug regime to eliminate the
infection. The re-infection rate in a developing country
such as Yemen is unknown and this too is under study.
Hepatitis
There are at least 5 different
viruses which cause acute hepatitis (types A, B, C, D and
E). In a recent study of 78 adult acute cases with
jaundice from Ta’iz and Sana’a, we found types B and E
accounted for 41%. To our great surprise in 51% of cases
we could not find a viral cause despite using the most
sophisticated laboratory methods. There must either be an
unknown virus responsible or some environmental toxin.
Clearly further work is needed.
Certain types of viral hepatitis
(particularly types B and C) have the propensity to become
chronic and may cause cirrhosis. Chronic hepatitis B is
very prevalent in Yemen. We found about 20% of apparently
healthy people were carrying the virus (compared with 1
per 1000 in UK). It may be transmitted from mother to
child or by scratches, needles and transfusions. It is
entirely preventable by vaccination, but this is not
generally available in Yemen due to its cost.
Chronic hepatitis C is also
prevalent in Yemen and an important cause of cirrhosis and
liver cancer. It is transmitted by similar routes to
hepatitis B. We found about 2% of apparently healthy
individuals are infected. There is presently no vaccine.
The strain of virus found in Yemen (Type 4) is
particularly resistant to currently available treatment.
Yemen has made
great strides forward in the past 10 years or so in
tackling its health problems, and I have every confidence -
given the excellence of the senior
medical leaders in the country - that
the pace of improvement will quicken. It is lack of
resources rather than skill and commitment which is
holding back the pace of progress.
(Dr Ian Murray-Lyon has
paid ten annual visits to the University of Sana’a
Medical College, principally to help with final MB exams.)
December 1997
|